ETS Awarded Technology Breakthrough Designation for Mirragen® Bioactive Glass with Premier, Inc.

Rolla, MO – September 15, 2025 — Engineered Tissue Solutions (ETS) has been awarded a national group purchasing agreement and Technology Breakthrough Designation for Reconstructive Skin Grafting Products with Premier, Inc. Premier offers Breakthrough Technology designations to innovations that offer a major advantage in terms of patient safety, clinical outcomes and operational efficiencies. Effective September 1, 2025, the new agreement allows Premier members, at their discretion, to take advantage of special pricing and terms pre-negotiated by Premier for Mirragen® and MirraSurg™, ETS’ borate-based bioactive glass wound matrices used for chronic and complex wounds.

“We are honored to receive a Breakthrough Technology award in the Reconstructive Skin Grafting category from Premier,” said A.J. Ford, CEO of ETS. “For wound care providers and their patients, this new agreement expands access to our groundbreaking bioactive glass technology. We are excited to offer this product to Premier members currently providing comprehensive limb salvage programs and wound care services to their communities and their patients.”

The “Reconstructive Skin Grafting Products” category, sometimes referred to as skin substitutes or CAMPs in the industry, is largely comprised of tissue-based products manufactured from human or other animal skin. These allografts and xenografts, respectively, have been used by wound care providers for decades. ETS is leading the newest subcategory of skin substitutes, synthetics, with pioneering innovations like Mirragen and MirraSurg. These bioactive glass products can be easily used in both inpatient and outpatient healthcare settings, and as synthetics, they don’t carry the same risk of viral transmission or microbial colonization that tissue-based products have. Moreover, patients with religious or cultural objections to human- or animal-based products can still be treated with ETS’ bioactive glass technology.

Premier is a leading technology-driven healthcare improvement company, providing solutions to two-thirds of all healthcare providers in the U.S. Playing a critical role in the rapidly evolving healthcare industry, Premier unites providers, suppliers, payers and policymakers to make healthcare better with national scale, smarter with actionable intelligence and faster with novel technologies. With integrated data and analytics, collaboratives, supply chain solutions, consulting and other services, Premier enables better care and outcomes at a lower cost.

Mirragen, the only borate-based bioactive glass wound matrix on the market, facilitates quality tissue formation without the traditional risk of infection tissue-based products have, all in an easy to use, versatile form factor.

About Engineered Tissue Solutions (ETS)

Engineered Tissue Solutions (ETS) is an innovative medical device company dedicated to transforming wound healing with its proprietary borate-based bioactive glass technology. As the developer of Mirragen®, the first FDA-cleared bioactive glass wound matrix, and MirraSurg™, designed specifically for surgical applications, ETS provides versatile solutions that facilitate quality tissue formation—without the traditional risk of infection tissue-based products have. These innovations are redefining the treatment of chronic wounds and complex soft tissue defects.

As a member of the Heraeus Group, a globally diversified family-owned technology company, ETS builds on a legacy of excellence and innovation. Learn more about the Heraeus Group at www.Heraeus.com.